3-Aminopyrazolo[1,5-a]pyrimidine

Name: 3-Aminopyrazolo[1,5-a]pyrimidine
Brand: ChemScene
Availability: InStock
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CAS No. 232600-93-0
Cat. No. CS-W006720
Purity≥98%
MDL No.MFCD00501923

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3-Aminopyrazolo[1,5-a]pyrimidine|CS-W006720

Structure of 232600-93-0

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General Information

CAS No. 232600-93-0
Cat. No. CS-W006720
Purity ≥98%
MDL No. MFCD00501923
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆N₄
Molecular Weight 134.14
Synonym(s) Pyrazolo[1,5-a]pyrimidin-3-amine
SMILES NC1=C2[N](N=C1)C=CC=N2

Description

3-Aminopyrazolo[1,5-a]pyrimidine features a fused heterocyclic core with a primary amine group enabling direct functionalization. This electron-rich scaffold integrates readily into medicinal chemistry campaigns, offering structural rigidity and enhanced solubility for target-directed synthesis.

Application

3-Aminopyrazolo[1,5-a]pyrimidine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to kinase inhibitors and other bioactive scaffolds. Its amino group facilitates direct derivatization via amidation, alkylation, or electrophilic substitution, while the fused pyrazolo[1,5-a]pyrimidine core exhibits robust bench stability and compatibility with standard coupling reactions. This compound functions as a key intermediate in the synthesis of purine analogs and exhibits favorable solubility for downstream processing.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 56.21
LogP 0.3115
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

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3-Aminopyrazolo[1,5-a]pyrimidine

CAS No. 232600-93-0

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