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Structure of 117519-06-9
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4-Chloro-6-(trifluoromethyl)pyridin-2-amine features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the chloro substituent enables direct functionalization. This pyridine scaffold integrates readily into pharmaceutical intermediates, offering robust reactivity under standard coupling conditions.
4-Chloro-6-(trifluoromethyl)pyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. The chloro group facilitates reliable C–C and C–N bond formation under standard conditions, while the trifluoromethyl moiety imparts enhanced metabolic stability and lipophilicity. Its bench-stable nature and compatibility with diverse functional groups make it ideal for parallel synthesis campaigns and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: