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Structure of 1132666-81-9
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This boronic acid features a difluorinated phenolic scaffold enabling robust Suzuki-Miyaura coupling under standard conditions. The ortho-hydroxyl group enhances reactivity and facilitates chelation in transition metal catalysis, while the electron-withdrawing fluorine substituents improve stability and modulate electrophilicity.
(3,5-Difluoro-4-hydroxyphenyl)boronic acid serves as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of fluorinated aryl scaffolds. The ortho-difluoro substitution enhances metabolic stability and modulates electronic properties in bioactive molecules. Its boronic acid functionality offers excellent bench stability, mild reaction conditions, and compatibility with diverse functional groups, facilitating rapid access to complex heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P261-P280-P304+P340-P405
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Lot numbers can be found on the outside label of a product: