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CS-W001157 4
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5H,6H,7H-Pyrrolo[1,2-a]imidazol-7-ol

  • CAS No. 112513-79-8

  • Cat. No. CS-0028385
  • Purity≥97%
  • MDL No.MFCD18821701

*For research and further manufacturing use only, not for direct human use.

5H,6H,7H-Pyrrolo[1,2-a]imidazol-7-ol|CS-0028385

Structure of 112513-79-8

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General Information

  • CAS No. 112513-79-8
  • Cat. No. CS-0028385
  • Purity ≥97%
  • MDL No. MFCD18821701
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol
  • SMILES OC1CCN2C=CN=C21

Description

5H,6H,7H-Pyrrolo[1,2-a]imidazol-7-ol is a heterocyclic scaffold featuring a fused imidazole-pyrrole core with a phenolic hydroxyl group at the 7-position. This configuration imparts enhanced solubility and hydrogen-bonding capacity, enabling direct incorporation into bioactive molecule designs. The compound exhibits bench-stable behavior under standard conditions and serves as a robust building block for targeted synthetic applications in medicinal chemistry and chemical biology.

Application

5H,6H,7H-Pyrrolo[1,2-a]imidazol-7-ol serves as a valuable heterocyclic building block for medicinal chemistry applications, offering a rigid, nitrogen-rich scaffold with defined regiochemistry. The hydroxyl group at the 7-position provides a site for derivatization while maintaining compatibility with standard coupling and functionalization protocols. Its stability under common reaction conditions facilitates incorporation into complex molecular architectures relevant to kinase inhibitors and other bioactive compounds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.3202
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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