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CS-W001157 4
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(S)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol

  • CAS No. 1221187-74-1

  • Cat. No. CS-0135854
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol|CS-0135854

Structure of 1221187-74-1

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General Information

  • CAS No. 1221187-74-1
  • Cat. No. CS-0135854
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) None
  • SMILES O[C@H]1CCN2C=CN=C21

Description

This chiral heterocycle features a fused pyrroloimidazole core with a hydroxyl group at the 7-position, offering a rigid scaffold for medicinal chemistry applications. The (S)-configuration ensures stereochemical precision in target-directed synthesis, while the hydroxyl moiety enables hydrogen bonding and further derivatization.

Application

(S)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of imidazole-fused scaffolds with defined stereochemistry. Its hydroxyl group facilitates downstream functionalization, while the stable dihydro scaffold exhibits excellent bench stability and compatibility with common coupling conditions. The compound functions effectively in transition-metal-catalyzed transformations and is well-suited for parallel library synthesis targeting kinase inhibitors and other bioactive molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.3202
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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