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CS-W001157 4
Total: USD 88.00

(2-Methylthiazol-5-yl)methanol

  • CAS No. 56012-38-5

  • Cat. No. CS-0152781
  • Purity≥96%
  • MDL No.MFCD12912988

*For research and further manufacturing use only, not for direct human use.

(2-Methylthiazol-5-yl)methanol|CS-0152781

Structure of 56012-38-5

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General Information

  • CAS No. 56012-38-5
  • Cat. No. CS-0152781
  • Purity ≥96%
  • MDL No. MFCD12912988
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇NOS
  • Molecular Weight 129.18
  • Synonym(s) 2-Methylthiazole-5-methanol
  • SMILES CC1=NC=C(CO)S1

Description

This bench-stable thiazole derivative features a methyl-substituted heterocyclic core paired with a reactive hydroxymethyl group. The para-positioned methanol functionality enables straightforward derivatization in synthetic transformations, while the electron-rich thiazole ring enhances stability and solubility in polar organic solvents. Ideal for building complex heterocyclic scaffolds in medicinal chemistry applications.

Application

(2-Methylthiazol-5-yl)methanol serves as a versatile building block for thiazole-based scaffolds in medicinal chemistry and materials science. Its benzylic alcohol functionality enables direct functionalization via oxidation, protection, or coupling reactions. The molecule exhibits good bench stability and compatibility with standard synthetic protocols, facilitating efficient incorporation into complex heterocyclic architectures and enabling access to diverse bioactive analogs through well-established transformations.

Synthesis

  • Route1

    References

    • Abbott Laboratories Patent: US5455351 A1, 1995 ; US 5455351 A
  • Route2

    References

    • US4032643 A1, ;
  • Route3
    • null|null
      50-00-0
    • In-stock
      2-Methylthiazole|CS-W002260
      3581-87-1
    • ~%
    • In-stock
      (2-Methylthiazol-5-yl)methanol|CS-0152781
      56012-38-5
    • 2-(1,3-Thiazol-2-yl)ethan-1-ol|CS-0070511
      89323-88-6

    References

    • Bulletin de la Societe Chimique de France, , p. 4134 - 4143

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   0.94382
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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