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CS-W001157 4
Total: USD 88.00

H2N-PEG2-CH2COOtBu

  • CAS No. 1122484-77-8

  • Cat. No. CS-0116296
  • Purity≥97%
  • MDL No.MFCD24395885

*For research and further manufacturing use only, not for direct human use.

H2N-PEG2-CH2COOtBu|CS-0116296

Structure of 1122484-77-8

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General Information

  • CAS No. 1122484-77-8
  • Cat. No. CS-0116296
  • Purity ≥97%
  • MDL No. MFCD24395885
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁NO₄
  • Molecular Weight 219.28
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)COCCOCCN

Description

H2N-PEG2-CH2COOtBu features a short PEG spacer linking a primary amine to a tert-butyl ester, enabling selective conjugation under mild conditions. This bifunctional scaffold supports efficient coupling reactions while the protected carboxyl group remains stable during handling and storage.

Application

H2N-PEG2-CH2COOtBu serves as a versatile bifunctional building block for peptide and protein conjugation, combining a stable tert-butyl ester with a terminal primary amine. The PEG2 spacer enhances solubility and reduces aggregation, while the ester group enables selective coupling under mild conditions. This reagent facilitates efficient solid-phase synthesis and bioconjugation workflows, offering excellent bench stability and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   70.78
  • LogP   0.32
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   7

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