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CS-W001157 4
Total: USD 88.00

H2N-PEG2-CH2COOH hydrochloride

  • CAS No. 134979-01-4

  • Cat. No. CS-0097751
  • Purity≥97%
  • MDL No.MFCD11865374

*For research and further manufacturing use only, not for direct human use.

H2N-PEG2-CH2COOH hydrochloride|CS-0097751

Structure of 134979-01-4

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General Information

  • CAS No. 134979-01-4
  • Cat. No. CS-0097751
  • Purity ≥97%
  • MDL No. MFCD11865374
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClNO₄
  • Molecular Weight 199.63
  • Synonym(s) None
  • SMILES O=C(COCCOCCN)O.Cl

Description

This hydrochloride salt features a polyether chain terminating in a primary amine, offering enhanced solubility and stability in aqueous media. The zwitterionic character facilitates efficient conjugation in bioconjugation workflows and enables robust labeling of biomolecules under physiological conditions.

Application

2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride serves as a versatile bifunctional building block featuring a primary amine and a carboxylic acid moiety, enabling conjugation or derivatization in peptide synthesis and polymer chemistry. The polyether chain imparts solubility and metabolic stability, while the hydrochloride salt enhances handling and storage stability. It functions effectively in aqueous and polar organic media, facilitating efficient coupling reactions with activated esters or aldehydes under mild conditions.

Synthesis

  • Route1

    References

    • Carbohydrate Research, , vol. 88, p. 213 - 222
  • Route2
    • PEG3-I|CS-0439102
      62573-16-4
    • ~%
    • In-stock
      H2N-PEG2-CH2COOH hydrochloride|CS-0097751
      134979-01-4

    References

    • Carbohydrate Research, , vol. 88, p. 213 - 222
  • Route3
    • 2-{2-[2-(2-Hydroxyethoxy)ethoxy]ethyl}isoindole-1,3-dione|CS-0212967
      75001-08-0
    • ~%
    • In-stock
      H2N-PEG2-CH2COOH hydrochloride|CS-0097751
      134979-01-4

    References

    • Carbohydrate Research, , vol. 88, p. 213 - 222

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   81.78
  • LogP   -0.5153
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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