Amino-PEG4-C1-Boc

Name: Amino-PEG4-C1-Boc
Brand: ChemScene
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CAS No. 864680-64-8
Cat. No. CS-B1625
Purity≥96%
MDL No.MFCD28122943

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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General Information

CAS No. 864680-64-8
Cat. No. CS-B1625
Purity ≥96%
MDL No. MFCD28122943
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₂₉NO₆
Molecular Weight 307.38
Synonym(s) None
SMILES NCCOCCOCCOCCOCC(OC(C)(C)C)=O

Description

Amino-PEG4-C1-Boc features a terminal amine tethered via a four-ethylene glycol unit to a C1 spacer, capped with a Boc protecting group. This design enables orthogonal functionalization in peptide synthesis and bioconjugation workflows. The PEG4 segment enhances solubility while the Boc moiety ensures stability during handling and storage.

Application

Amino-PEG4-C1-Boc serves as a versatile bifunctional building block for peptide and oligonucleotide conjugation, combining the solubility and flexibility of PEG4 with the orthogonal reactivity of the Boc group. The primary amine enables efficient coupling to carboxylic acid-containing substrates, while the C1 linker provides minimal steric hindrance. The Boc group offers stable protection under basic conditions and can be selectively removed with mild acid, facilitating downstream functionalization in multi-step syntheses.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 89.24
LogP 0.3532
H_Acceptors 7
H_Donors 1
Rotatable_Bonds 13

Other Classifications

Life Science PROTAC PROTAC Linker

Life Science Linker Amino PEG

Building Blocks Skeleton Fatty chain compounds

Building Blocks Functional Group Boc

Building Blocks Functional Group PEG

Building Blocks Functional Group Amine

Building Blocks Functional Group Ester

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

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Amino-PEG4-C1-Boc

CAS No. 864680-64-8

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