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Structure of 111043-48-2
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3-Hydroxy-1-methylazetidine is a strained, four-membered heterocyclic amine featuring a hydroxyl group at the 3-position and a methyl substituent at nitrogen. This configuration imparts enhanced solubility and nucleophilicity, enabling efficient incorporation into bioactive molecules. The compound serves as a conformationally restricted scaffold in medicinal chemistry, facilitating targeted interactions with biological targets. Its bench-stable nature supports reliable handling under standard conditions.
3-Hydroxy-1-methylazetidine serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its strained azetidine core enhances metabolic stability and membrane permeability, while the hydroxyl and methyl groups offer orthogonal handles for derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, supporting its use in diverse coupling reactions and scaffold elaboration.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: