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1-Methyl-3-azetidinol Hydrochloride

  • CAS No. 26687-49-0

  • Cat. No. CS-0040831
  • Purity≥95%
  • MDL No.MFCD16605978

*For research and further manufacturing use only, not for direct human use.

1-Methyl-3-azetidinol Hydrochloride|CS-0040831

Structure of 26687-49-0

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General Information

  • CAS No. 26687-49-0
  • Cat. No. CS-0040831
  • Purity ≥95%
  • MDL No. MFCD16605978
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO
  • Molecular Weight 123.58
  • Synonym(s) 3-Hydroxy-1-methylazetidine hydrochloride
  • SMILES OC1CN(C)C1.Cl

Description

1-Methyl-3-azetidinol Hydrochloride offers a strained, electron-rich azetidine core ideal for nucleophilic functionalization. This bench-stable derivative integrates readily into medicinal chemistry scaffolds, delivering enhanced solubility and metabolic stability in bioactive molecule design.

Application

1-Methyl-3-azetidinol Hydrochloride serves as a versatile synthetic building block for medicinal chemistry, enabling efficient access to saturated β-lactam frameworks and nitrogen-containing heterocycles. Its well-defined reactivity facilitates nucleophilic substitution and cyclization reactions under mild conditions, with the hydrochloride salt offering enhanced bench stability and ease of handling. The molecule’s functional group tolerance supports integration into multi-step syntheses, making it a practical choice for API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   -0.2855
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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