Methyl (R)-(+)-3-Bromoisobutyrate

Name: Methyl (R)-(+)-3-Bromoisobutyrate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 110556-33-7
Cat. No. CS-0130400
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl (R)-(+)-3-Bromoisobutyrate|CS-0130400

Structure of 110556-33-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 110556-33-7
Cat. No. CS-0130400
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₉BrO₂
Molecular Weight 181.03
Synonym(s) Methyl (R)-(+)-3-bromo-2-methylpropionate
SMILES C[C@H](C(OC)=O)CBr

Description

Methyl (R)-(+)-3-bromoisobutyrate is a chiral building block featuring a stereodefined bromomethyl group adjacent to a tertiary carbon. This configuration enables selective functionalization in asymmetric synthesis, particularly in the construction of enantiopure pharmaceutical intermediates. The ester moiety enhances solubility and reactivity under standard conditions, while the benzylic-like bromide facilitates nucleophilic substitution with minimal elimination. Bench-stable and moisture-tolerant, this reagent streamlines access to complex alkylated frameworks in medicinal chemistry workflows.

Application

Methyl (R)-(+)-3-bromoisobutyrate serves as a chiral building block for asymmetric synthesis, enabling stereoselective transformations via its reactive bromomethyl group. Its bench-stable nature and compatibility with palladium-catalyzed cross-couplings facilitate efficient construction of complex molecular architectures. The methyl ester functionality supports straightforward derivatization, making it a practical choice for medicinal chemistry campaigns requiring enantiopure intermediates.

Synthesis

Route1
- In-stock
  
  80657-57-4
- ~74%
- In-stock
  
  110556-33-7
References
- Journal of Organic Chemistry USSR (English Translation), , vol. 26, # 2.2 p. 364 - 369 Zhurnal Organicheskoi Khimii, , vol. 26, # 2 p. 425 - 432
Route2
- 142402-78-6
- ~79%
- In-stock
  
  110556-33-7
References
- Tetrahedron Asymmetry, , vol. 9, # 7 p. 1131 - 1135
Route3
- In-stock
  
  72657-23-9
- ~68%
- In-stock
  
  110556-33-7
References
- Tetrahedron Letters, , vol. 28, # 3 p. 337 - 340

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 26.3
LogP 1.1904
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

Methyl (R)-(+)-3-Bromoisobutyrate sigmaMethyl (R)-(+)-3-Bromoisobutyrate manufacturerMethyl (R)-(+)-3-Bromoisobutyrate priceMethyl (R)-(+)-3-Bromoisobutyrate structureMethyl (R)-(+)-3-Bromoisobutyrate SDSbuy Methyl (R)-(+)-3-BromoisobutyrateMethyl (R)-(+)-3-Bromoisobutyrate supplierMethyl (R)-(+)-3-Bromoisobutyrate usesMethyl (R)-(+)-3-Bromoisobutyrate molecular weightprice of Methyl (R)-(+)-3-BromoisobutyrateMethyl (R)-(+)-3-Bromoisobutyrate chemical name formula of Methyl (R)-(+)-3-Bromoisobutyrate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl (R)-(+)-3-Bromoisobutyrate

CAS No. 110556-33-7

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words