5-Bromo-4-chloro-1H-indazole

Name: 5-Bromo-4-chloro-1H-indazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1082041-90-4
Cat. No. CS-0040204
Purity≥97%
MDL No.MFCD11007933

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1082041-90-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1082041-90-4
Cat. No. CS-0040204
Purity ≥97%
MDL No. MFCD11007933
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrClN₂
Molecular Weight 231.48
Synonym(s) 1H-Indazole,5-bromo-4-chloro
SMILES ClC1=C(Br)C=CC2=C1C=NN2

Description

5-Bromo-4-chloro-1H-indazole is a halogenated indazole scaffold featuring complementary reactive sites for downstream functionalization. The bromine at the 5-position and chlorine at the 4-position enable selective cross-coupling reactions under palladium catalysis. This electron-deficient heterocycle serves as a robust building block in medicinal chemistry and materials science, offering enhanced stability and predictable reactivity profiles in synthetic workflows.

Application

5-Bromo-4-chloro-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromo and chloro substituents offer orthogonal functionalization potential, facilitating sequential derivatization. Bench-stable and readily purified by crystallization, it functions effectively in the construction of complex heterocyclic scaffolds relevant to kinase inhibitor development and other bioactive molecule synthesis.

Synthesis

Route1
- In-stock
  
  627531-47-9
- ~%
- In-stock
  
  1082041-90-4
References
- US2012/71535 A1, ; Page/Page column 56-57 ;
Route2
- In-stock
  
  87-60-5
- ~%
- In-stock
  
  1082041-90-4
References
- US2012/71535 A1, ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 28.68
LogP 2.9788
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Indazole compounds

Key Words

5-Bromo-4-chloro-1H-indazole sigma5-Bromo-4-chloro-1H-indazole manufacturer5-Bromo-4-chloro-1H-indazole price5-Bromo-4-chloro-1H-indazole structure5-Bromo-4-chloro-1H-indazole SDSbuy 5-Bromo-4-chloro-1H-indazole5-Bromo-4-chloro-1H-indazole supplier5-Bromo-4-chloro-1H-indazole uses5-Bromo-4-chloro-1H-indazole molecular weightprice of 5-Bromo-4-chloro-1H-indazole5-Bromo-4-chloro-1H-indazole chemical name formula of 5-Bromo-4-chloro-1H-indazole

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-4-chloro-1H-indazole

CAS No. 1082041-90-4

Recommended Products