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5-Bromo-6-chloro-1H-indazole

  • CAS No. 1260382-77-1

  • Cat. No. CS-0041812
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-6-chloro-1H-indazole|CS-0041812

Structure of 1260382-77-1

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General Information

  • CAS No. 1260382-77-1
  • Cat. No. CS-0041812
  • Purity ≥97%
  • MDL No. None
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrClN₂
  • Molecular Weight 231.48
  • Synonym(s) 6-chloro-5-bromoindazole
  • SMILES ClC1=CC2=C(C=C1Br)C=NN2

Description

5-Bromo-6-chloro-1H-indazole features a fused bicyclic core with complementary halogen substituents enabling selective functionalization. The electron-deficient indazole scaffold supports transition metal-catalyzed cross-coupling, while the bromo and chloro groups offer orthogonal reactivity for sequential derivatization. This platform delivers structural diversity in medicinal chemistry and materials synthesis under standard conditions.

Application

5-Bromo-6-chloro-1H-indazole serves as a versatile building block for the synthesis of biologically active heterocycles, enabling direct functionalization at multiple positions via Pd-catalyzed cross-coupling. Its complementary halogenation pattern offers orthogonal reactivity for sequential derivatization, while maintaining bench stability and compatibility with standard purification protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.9788
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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