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CS-W001157 4
Total: USD 88.00

3-Chloro-2-methylphenylamine

  • CAS No. 87-60-5

  • Cat. No. CS-D1106
  • Purity≥98%
  • MDL No.MFCD00007766

*For research and further manufacturing use only, not for direct human use.

3-Chloro-2-methylphenylamine|CS-D1106

Structure of 87-60-5

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General Information

  • CAS No. 87-60-5
  • Cat. No. CS-D1106
  • Purity ≥98%
  • MDL No. MFCD00007766
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClN
  • Molecular Weight None
  • Synonym(s) fast scarlet TR base
  • SMILES NC1=CC=CC(Cl)=C1C

Description

3-Chloro-2-methylphenylamine features a chlorinated benzene ring with adjacent methyl and amino substituents, delivering enhanced electron density at the para-position. This configuration enables efficient coupling in cross-coupling reactions and facilitates direct functionalization in pharmaceutical intermediates. The compound exhibits bench-stable handling characteristics and compatibility with diverse reaction conditions.

Application

3-Chloro-2-methylphenylamine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of both chloro and methyl substituents on an aromatic amine scaffold. Its stability under standard reaction conditions and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient diversification. The compound functions effectively in electrophilic substitution and reductive amination workflows, offering reliable access to substituted benzene derivatives with defined regiochemistry.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H317-H411
Precautionary Statements : P261-P264-P270-P272-P273-P280-P301+P310-P302+P352-P312-P330-P362+P364-P363-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.23062
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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