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CS-W001157 4
Total: USD 88.00

3,6-Dichloro-2-methylaniline

  • CAS No. 62077-26-3

  • Cat. No. CS-0342996
  • Purity≥98%
  • MDL No.MFCD20699076

*For research and further manufacturing use only, not for direct human use.

3,6-Dichloro-2-methylaniline|CS-0342996

Structure of 62077-26-3

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General Information

  • CAS No. 62077-26-3
  • Cat. No. CS-0342996
  • Purity ≥98%
  • MDL No. MFCD20699076
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇Cl₂N
  • Molecular Weight 176.04
  • Synonym(s) 3,6-Dichloro-2-methylbenzenamine
  • SMILES NC1=C(Cl)C=CC(Cl)=C1C

Description

3,6-Dichloro-2-methylaniline features a chlorine-substituted aromatic ring with a methyl group at the ortho position, delivering enhanced electron-withdrawal and steric shielding. This configuration supports stable coupling reactions in pharmaceutical intermediates and agrochemical synthesis under standard conditions.

Application

3,6-Dichloro-2-methylaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering a highly functionalized aromatic scaffold with orthogonal reactivity. The electron-deficient aryl ring facilitates electrophilic substitution, while the primary amine enables coupling reactions (e.g., Suzuki, Buchwald–Hartwig). Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring precise regiocontrol and compatibility with diverse protecting groups.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.88402
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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