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CS-W001157 4
Total: USD 88.00

1-(2-Bromoethyl)-4-methoxybenzene

  • CAS No. 14425-64-0

  • Cat. No. CS-0150393
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(2-Bromoethyl)-4-methoxybenzene|CS-0150393

Structure of 14425-64-0

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General Information

  • CAS No. 14425-64-0
  • Cat. No. CS-0150393
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁BrO
  • Molecular Weight 215.09
  • Synonym(s) p-Methoxyphenylethyl bromide
  • SMILES COC1=CC=C(C=C1)CCBr

Description

1-(2-Bromoethyl)-4-methoxybenzene features a bromoethyl chain appended to a methoxy-substituted benzene ring, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. The electron-donating methoxy group enhances reactivity while maintaining stability under standard conditions.

Synthesis

  • Route1

    References

    • Eisai Co., Ltd. Patent: US2002/19531 A1, 2002 ; US 20020019531 A1
  • Route2

    References

    • Dehmel, Florian; Ciossek, Thomas; Maier, Thomas; Weinbrenner, Steffen; Schmidt, Beate; Zoche, Martin; Beckers, Thomas Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 17 p. 4746 - 4752
  • Route3

    References

    • Dao, Duc Hai; Okamura, Mutsuo; Akasaka, Takeshi; Kawai, Yasushi; Hida, Kouichi; Ohno, Atsuyoshi Tetrahedron Asymmetry, 1998 , vol. 9, # 15 p. 2725 - 2737

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   2.6326
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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