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CS-W001157 4
Total: USD 88.00

1-(2-Bromoethyl)-4-chlorobenzene

  • CAS No. 6529-53-9

  • Cat. No. CS-W009513
  • Purity≥95%
  • MDL No.MFCD00634271

*For research and further manufacturing use only, not for direct human use.

1-(2-Bromoethyl)-4-chlorobenzene|CS-W009513

Structure of 6529-53-9

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General Information

  • CAS No. 6529-53-9
  • Cat. No. CS-W009513
  • Purity ≥95%
  • MDL No. MFCD00634271
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BrCl
  • Molecular Weight 219.51
  • Synonym(s) p-Chloro-.beta.-phenethyl bromide
  • SMILES ClC1=CC=C(CCBr)C=C1

Description

1-(2-Bromoethyl)-4-chlorobenzene features a bromoethyl chain appended to a para-chlorinated benzene ring, enabling efficient coupling reactions in synthetic pathways. This bifunctional architecture supports site-specific derivatization in medicinal chemistry and materials synthesis. The compound exhibits robust stability under standard handling conditions and facilitates straightforward incorporation into complex molecular frameworks via nucleophilic substitution.

Synthesis

  • Route1

    References

    • Moriya, Toshimitsu; Yoneda, Shinichiro; Kawana, Keita; Ikeda, Reiko; Konakahara, Takeo; Sakai, Norio Organic Letters, 2012 , vol. 14, # 18 p. 4842 - 4845,4
  • Route2

    References

    • Weigl, Ulrich; Porstmann, Frank; Straessler, Christoph; Ulmer, Lars; Koetz, Ulf Patent: US2009/143576 A1, 2009 ; Location in patent: Page/Page column 2; 9-10 ;
  • Route3
    • null|null
      146404-41-3
    • ~84%
    • In-stock
      1-(2-Bromoethyl)-4-chlorobenzene|CS-W009513
      6529-53-9
    • In-stock
      4-Methylbenzene-1-sulfonyl bromide|CS-0238690
      1950-69-2

    References

    • Collazo, Luis R.; Guziec, Frank S.; Hu, Wei-Xiao Jr.; Pankayatselvan, Ratnadevi Tetrahedron Letters, 1994 , vol. 35, # 43 p. 7911 - 7914

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H318-H411
Precautionary Statements : P264-P270-P273-P280-P330-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.2774
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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