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CS-W001157 4
Total: USD 88.00

Bromomalonic acid diethyl ester

  • CAS No. 685-87-0

  • Cat. No. CS-B0964
  • Purity≥96%
  • MDL No.MFCD00009138

*For research and further manufacturing use only, not for direct human use.

Bromomalonic acid diethyl ester|CS-B0964

Structure of 685-87-0

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General Information

  • CAS No. 685-87-0
  • Cat. No. CS-B0964
  • Purity ≥96%
  • MDL No. MFCD00009138
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁BrO₄
  • Molecular Weight 239.06
  • Synonym(s) Diethyl 2-bromo-1,3-propanedioate; Diethyl 2-bromomalonate; Diethyl 2-bromopropanedioate; Diethyl bromomalonate; diethyl bromopropanedioate
  • SMILES O=C(OCC)C(Br)C(OCC)=O

Description

Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

Synthesis

  • Route1
    • null|null
      105-53-3
    • ~97%
    • In-stock
      Bromomalonic acid diethyl ester|CS-B0964
      685-87-0

    References

    • Martinkus; Tann; Gould Tetrahedron, 1983 , vol. 39, # 21 p. 3493 - 3505
  • Route2
    • null|null
      105-53-3
    • ~85%
    • null|null
      631-22-1
    • In-stock
      Bromomalonic acid diethyl ester|CS-B0964
      685-87-0

    References

    • Russian Journal of Organic Chemistry, , vol. 30, # 7.1 p. 1042 - 1044 Zhurnal Organicheskoi Khimii, , vol. 30, # 7 p. 986 - 988
  • Route3
    • null|null
      631-22-1
    • ~0%
    • null|null
      599-99-5
    • In-stock
      Bromomalonic acid diethyl ester|CS-B0964
      685-87-0

    References

    • Mebane, Robert C.; Smith, Keegan M.; Rucker, Darlene R.; Foster, Michael P. Tetrahedron Letters, 1999 , vol. 40, # 8 p. 1459 - 1462

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   0.8761
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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