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CS-W001157 4
Total: USD 88.00

(6-Bromopyridin-3-yl)methanamine

  • CAS No. 120740-10-5

  • Cat. No. CS-W005988
  • Purity≥95%
  • MDL No.MFCD06738744

*For research and further manufacturing use only, not for direct human use.

(6-Bromopyridin-3-yl)methanamine|CS-W005988

Structure of 120740-10-5

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General Information

  • CAS No. 120740-10-5
  • Cat. No. CS-W005988
  • Purity ≥95%
  • MDL No. MFCD06738744
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂
  • Molecular Weight 187.04
  • Synonym(s) 6-bromo-3-Pyridinemethanamine
  • SMILES NCC1=CC=C(Br)N=C1

Description

(6-Bromopyridin-3-yl)methanamine features a brominated pyridine core with a primary amine tethered to the 3-position, enabling direct functionalization in cross-coupling and amine coupling reactions. This bench-stable, moisture-tolerant building block integrates readily into pharmaceutical intermediates and advanced synthetic scaffolds.

Application

(6-Bromopyridin-3-yl)methanamine serves as a versatile building block for the synthesis of functionalized pyridine derivatives, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. Its bromo group facilitates efficient C–C and C–N bond formation, while the primary amine functions as a handle for further derivatization or conjugation. The compound exhibits good bench stability and ease of purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Journal of Medicinal Chemistry, , vol. 56, # 15 p. 6234 - 6247
  • Route2
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      120740-11-6
    • ~%
    • In-stock
      (6-Bromopyridin-3-yl)methanamine|CS-W005988
      120740-10-5

    References

    • Journal of Agricultural and Food Chemistry, , vol. 56, # 1 p. 204 - 212
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 56, # 15 p. 6234 - 6247

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.3028
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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