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Structure of 205744-15-6
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(2-Bromopyridin-3-yl)methanamine features a pyridine ring bearing a bromine at the 2-position and a primary amine attached via a methylene linker at the 3-position. This configuration enables direct functionalization in cross-coupling reactions, with the electron-deficient pyridine ring enhancing reactivity toward nucleophilic substitution. The compound exhibits bench-stable handling characteristics and serves as a key intermediate in medicinal chemistry for constructing bioactive heterocycles.
(2-Bromopyridin-3-yl)methanamine serves as a versatile building block for constructing pyridine-based heterocycles and pharmaceutical intermediates. Its bromine atom enables palladium-catalyzed cross-coupling reactions, while the primary amine functions as a handle for derivatization via acylation, alkylation, or cyclization. The compound exhibits good bench stability and is compatible with standard purification techniques, facilitating integration into multi-step synthetic sequences for medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: