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Structure of 1068471-18-0
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Methyl 3-(4-Ethynylphenyl)propanoate features a conjugated ethynyl group directly linked to a phenyl ring, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC). This alkyne functionality integrates readily into bioconjugation workflows and polymer architectures. The methyl ester provides stability and handles well under standard bench conditions.
Methyl 3-(4-Ethynylphenyl)propanoate serves as a versatile building block for transition-metal-catalyzed coupling reactions, enabling efficient access to conjugated aryl-alkyne architectures. Its terminal alkyne functionality facilitates Sonogashira and Glaser-type couplings, while the ester group supports subsequent transformations including hydrolysis and derivatization. The compound exhibits excellent bench stability, mild handling requirements, and straightforward purification by distillation or flash chromatography, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: