Lot numbers can be found on the outside label of a product:
Methyl 5-bromoindole-7-carboxylate
-
CAS No. 860624-89-1
- Cat. No. CS-W018681
- Purity≥95%
- MDL No.MFCD08062511
*For research and further manufacturing use only, not for direct human use.
Structure of 860624-89-1
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 860624-89-1
- Cat. No. CS-W018681
- Purity ≥95%
- MDL No. MFCD08062511
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₈BrNO₂
- Molecular Weight 254.08
- Synonym(s) methyl 5-bromo-1H-indole-7-carboxylate
- SMILES O=C(C1=CC(Br)=CC2=C1NC=C2)OC
Description
Methyl 5-bromoindole-7-carboxylate is a brominated indole derivative featuring a methyl ester at the C7 position. This compound serves as a key intermediate in the synthesis of bioactive heterocycles, offering enhanced reactivity in cross-coupling and functionalization reactions. The electron-deficient nature of the bromo group facilitates palladium-catalyzed transformations, while the ester moiety enables further derivatization. Its bench-stable form supports reliable handling in synthetic workflows.
Application
Methyl 5-bromoindole-7-carboxylate serves as a versatile building block for the synthesis of substituted indoles and heterocyclic scaffolds. The bromo group enables palladium-catalyzed cross-coupling reactions, while the ester functionality supports selective transformations under mild conditions. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
Synthesis
-
Route1
-
In-stock
860624-90-4 -
74-88-4 - ~91%
-
In-stock
860624-89-1
References
-
SMITHKLINE BEECHAM CORPORATION Patent: WO2008/118724 A1, 2008 ; Location in patent: Page/Page column 69-70 ; WO 2008/118724 A1
-
-
Route2
-
860624-88-0 - ~90%
-
In-stock
860624-89-1
References
-
SMITHKLINE BEECHAM CORPORATION Patent: WO2008/118724 A1, 2008 ; Location in patent: Page/Page column 69 ; WO 2008/118724 A1
-
-
Route3
-
875305-09-2 - ~25%
-
In-stock
860624-89-1
References
-
Conte-Mayweg, Aurelia; Kuehne, Holger; Luebbers, Thomas; Maugeais, Cyrille; Mueller, Werner; Pflieger, Philippe Patent: US2006/30613 A1, 2006 ; Location in patent: Page/Page column 22 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 42.09
- LogP 2.717
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 5-bromoindole-7-carboxylate sigmaMethyl 5-bromoindole-7-carboxylate manufacturerMethyl 5-bromoindole-7-carboxylate priceMethyl 5-bromoindole-7-carboxylate structureMethyl 5-bromoindole-7-carboxylate SDSbuy Methyl 5-bromoindole-7-carboxylateMethyl 5-bromoindole-7-carboxylate supplierMethyl 5-bromoindole-7-carboxylate usesMethyl 5-bromoindole-7-carboxylate molecular weightprice of Methyl 5-bromoindole-7-carboxylateMethyl 5-bromoindole-7-carboxylate chemical name formula of Methyl 5-bromoindole-7-carboxylate