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Structure of 1060810-66-3
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4-chloro-6-(trifluoromethyl)nicotinic acid features a trifluoromethyl group that enhances electron-withdrawing character and metabolic stability, while the chloro substituent provides a site for further functionalization. This scaffold integrates readily into bioactive molecules, particularly in medicinal chemistry and agrochemical development.
4-Chloro-6-(trifluoromethyl)nicotinic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its orthogonal functionalization profile—combining a reactive chloro group and a stable trifluoromethyl-substituted pyridine core—facilitates palladium-catalyzed couplings and direct arylation reactions. The compound exhibits excellent bench stability and compatibility with common protecting group strategies, making it ideal for modular synthesis of pharmaceutical intermediates and agrochemical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: