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CS-W001157 4
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3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine

  • CAS No. 1160614-73-2

  • Cat. No. CS-0051657
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine|CS-0051657

Structure of 1160614-73-2

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General Information

  • CAS No. 1160614-73-2
  • Cat. No. CS-0051657
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₁BN₂O₂
  • Molecular Weight 248.13
  • Synonym(s) None
  • SMILES CC1(C)OB(OC1(C)C)C1=C2CCCCN2N=C1

Description

This tetrahydropyrazolopyridine boronate integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, delivering functionalized heterocycles with high efficiency. The stable dioxaborolane moiety enables reliable coupling under mild conditions, while the fused pyrazolo[1,5-a]pyridine core provides a rigid, electron-rich scaffold for drug discovery applications.

Application

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. Its tetrahydropyrazolo scaffold provides a rigid, nitrogen-rich heterocyclic core with favorable solubility and bench stability. The pinacol boronate group enables reliable coupling under mild conditions, tolerating diverse functional groups and facilitating the construction of complex molecular architectures in medicinal chemistry and materials science workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.28
  • LogP   1.5186
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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