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CS-W001157 4
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(S)-(Tetrahydrofuran-3-yl)methanamine

  • CAS No. 1048962-84-0

  • Cat. No. CS-0053039
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-(Tetrahydrofuran-3-yl)methanamine|CS-0053039

Structure of 1048962-84-0

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General Information

  • CAS No. 1048962-84-0
  • Cat. No. CS-0053039
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) (3S)-Tetrahydro-3-furanmethanamine
  • SMILES NC[C@@H]1CCOC1

Description

(S)-(Tetrahydrofuran-3-yl)methanamine is a chiral building block featuring a stereodefined tetrahydrofuran ring fused to a primary amine. This configuration enables precise control in asymmetric synthesis, particularly in the construction of bioactive heterocycles and peptide mimetics. The molecule exhibits favorable solubility and stability under standard bench conditions, facilitating straightforward handling in medicinal chemistry workflows.

Application

(S)-(Tetrahydrofuran-3-yl)methanamine serves as a versatile chiral building block for synthesizing bioactive molecules, particularly in medicinal chemistry and asymmetric synthesis. Its tetrahydrofuran ring provides rigidity and stereoselective control, while the primary amine enables straightforward functionalization via acylation, alkylation, or coupling reactions. The compound exhibits good bench stability, ease of purification, and compatibility with common protecting group strategies, making it well-suited for iterative synthetic sequences and API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   -0.0184
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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