Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-2-(hydroxymethyl)pyridine

  • CAS No. 88139-91-7

  • Cat. No. CS-D0982
  • Purity≥96%
  • MDL No.MFCD04035597

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-(hydroxymethyl)pyridine|CS-D0982

Structure of 88139-91-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 88139-91-7
  • Cat. No. CS-D0982
  • Purity ≥96%
  • MDL No. MFCD04035597
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BrNO
  • Molecular Weight 188.02
  • Synonym(s) 5-Bromo-2-pyridinemethanol
  • SMILES OCC1=NC=C(Br)C=C1

Description

5-Bromo-2-(hydroxymethyl)pyridine features a pyridine ring functionalized with a bromo group at the 5-position and a hydroxymethyl substituent at the 2-position, enabling dual reactivity. This combination facilitates efficient coupling reactions in medicinal chemistry and materials synthesis. The hydroxymethyl group offers a handle for derivatization while maintaining compatibility with standard synthetic protocols.

Application

5-Bromo-2-(hydroxymethyl)pyridine serves as a versatile building block for heterocyclic synthesis, enabling efficient functionalization at the pyridine ring and hydroxymethyl side chain. Its bromo group facilitates Suzuki-Miyaura and Stille couplings, while the primary alcohol supports oxidation, protection, or direct derivatization. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for medicinal chemistry campaigns and process development.

Synthesis

  • Route1

    References

    • Neto, Carina; Oliveira, Maria Cristina; Gano, Lurdes; Marques, Fernanda; Thiemann, Thies; Santos, Isabel Journal of Inorganic Biochemistry, 2012 , vol. 111, p. 1 - 9
  • Route2
    • null|null
      31181-64-3
    • ~76%
    • In-stock
      5-Bromo-2-(hydroxymethyl)pyridine|CS-D0982
      88139-91-7

    References

    • ASTRAZENECA AB; NPS PHARMACEUTICALS, INC. Patent: WO2006/20879 A1, 2006 ; Location in patent: Page/Page column 114 ; WO 2006/020879 A1
  • Route3

    References

    • Bleicher, Konrad; Flohr, Alexander; Groebke Zbinden, Katrin; Gruber, Felix; Koerner, Matthias; Kuhn, Bernd; Peters, Jens-Uwe; Sarmiento, Rosa Maria Rodriguez Patent: US2011/306589 A1, 2011 ; Location in patent: Page/Page column 38 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.3364
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-2-(hydroxymethyl)pyridine sigma5-Bromo-2-(hydroxymethyl)pyridine manufacturer5-Bromo-2-(hydroxymethyl)pyridine price5-Bromo-2-(hydroxymethyl)pyridine structure5-Bromo-2-(hydroxymethyl)pyridine SDSbuy 5-Bromo-2-(hydroxymethyl)pyridine5-Bromo-2-(hydroxymethyl)pyridine supplier5-Bromo-2-(hydroxymethyl)pyridine uses5-Bromo-2-(hydroxymethyl)pyridine molecular weightprice of 5-Bromo-2-(hydroxymethyl)pyridine5-Bromo-2-(hydroxymethyl)pyridine chemical name formula of 5-Bromo-2-(hydroxymethyl)pyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label