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CS-W001157 4
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5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)pyridine

  • CAS No. 88139-92-8

  • Cat. No. CS-0457771
  • Molecule weight302.28
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)pyridine|CS-0457771

Structure of 88139-92-8

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General Information

  • CAS No. 88139-92-8
  • Cat. No. CS-0457771
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀BrNOSi
  • Molecular Weight 302.28
  • Synonym(s) 5-Bromo-2-({[t-butyl(dimethyl)silyl]oxy}methyl)pyridine
  • SMILES C[Si](OCC1=NC=C(Br)C=C1)(C(C)(C)C)C

Synthesis

  • Route1

    References

    • Beves, Jonathon E.; Campbell, Christopher J.; Leigh, David A.; Pritchard, Robin G. Angewandte Chemie - International Edition, 2013 , vol. 52, # 25 p. 6464 - 6467 Angew. Chem., 2013 , vol. 125, # 25 p. 6592 - 6595,4
  • Route2
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    • 5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)pyridine|CS-0457771
      88139-92-8

    References

    • Guthikonda; Cama; Quesada; Woods; Salzmann; Christensen Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 871 - 880
  • Route3

    References

    • Guthikonda; Cama; Quesada; Woods; Salzmann; Christensen Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 871 - 880

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   4.3659
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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