Lot numbers can be found on the outside label of a product:
Imidazo[1,2-a]pyridin-7-amine
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CAS No. 421595-81-5
- Cat. No. CS-0049341
- Purity≥98%
- MDL No.MFCD11052644
*For research and further manufacturing use only, not for direct human use.
![Imidazo[1,2-a]pyridin-7-amine|CS-0049341](https://file.chemscene.com/productPIC/CS-0049341.gif)
Structure of 421595-81-5
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General Information
- CAS No. 421595-81-5
- Cat. No. CS-0049341
- Purity ≥98%
- MDL No. MFCD11052644
- Storage 4°C, protect from light, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₇N₃
- Molecular Weight None
- Synonym(s) Imidazo[1,2-a]pyridin-7-amine (9CI)
- SMILES NC1=CC2=NC=CN2C=C1
Description
Imidazo[1,2-a]pyridin-7-amine delivers a rigid, electron-rich heteroaromatic scaffold ideal for medicinal chemistry. This nitrogen-dense core integrates readily into kinase inhibitors and targeted therapeutics, offering enhanced binding affinity and metabolic stability under standard conditions.
Application
Imidazo[1,2-a]pyridin-7-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to biologically active scaffolds. Its nitrogen-rich framework supports diverse functionalization, exhibits favorable solubility and bench stability, and participates reliably in cross-coupling and electrophilic substitution reactions. This compound functions as a key intermediate in the synthesis of kinase inhibitors and other targeted therapeutics.
Synthesis
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Route1
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421596-48-7 - ~91%
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In-stock
421595-81-5
References
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Chezal, Jean M; Moreau, Emmanuel; Chavignon, Olivier; Gaumet, Vincent; Metin, Jacques; Blache, Yves; Diez, Anna; Fradera, Xavier; Luque, Javier; Teulade, Jean C Tetrahedron, 2002 , vol. 58, # 2 p. 295 - 307
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Route2
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![Ethyl Imidazo[1,2-a]pyridine-7-carboxylate|CS-0008732](https://file.chemscene.com/productPIC/CS-0008732.gif)
372147-49-4 - ~%
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In-stock
421595-81-5
References
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Chezal, Jean M; Moreau, Emmanuel; Chavignon, Olivier; Gaumet, Vincent; Metin, Jacques; Blache, Yves; Diez, Anna; Fradera, Xavier; Luque, Javier; Teulade, Jean C Tetrahedron, 2002 , vol. 58, # 2 p. 295 - 307
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Route3
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421595-79-1
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In-stock
421595-81-5
References
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Chezal, Jean M; Moreau, Emmanuel; Chavignon, Olivier; Gaumet, Vincent; Metin, Jacques; Blache, Yves; Diez, Anna; Fradera, Xavier; Luque, Javier; Teulade, Jean C Tetrahedron, 2002 , vol. 58, # 2 p. 295 - 307
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335-H332-H312
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 43.32
- LogP 0.9165
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 0
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Key Words
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