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CS-W001157 4
Total: USD 88.00

Tiglic acid

  • CAS No. 80-59-1

  • Cat. No. CS-W013715
  • Purity≥98%
  • MDL No.MFCD00066864

*For research and further manufacturing use only, not for direct human use.

Tiglic acid|CS-W013715

Structure of 80-59-1

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General Information

  • CAS No. 80-59-1
  • Cat. No. CS-W013715
  • Purity ≥98%
  • MDL No. MFCD00066864
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₂
  • Molecular Weight 100.12
  • Synonym(s) None
  • SMILES C/C=C(C)/C(O)=O

Application

Tiglic acid serves as a valuable chiral building block in synthetic organic chemistry, particularly for the construction of terpene-derived scaffolds and bioactive molecules. Its α,β-unsaturated carboxylic acid functionality enables reliable Michael additions, Diels–Alder reactions, and metal-catalyzed coupling processes. The molecule exhibits good bench stability and facilitates straightforward derivatization, making it a practical choice for medicinal chemistry and natural product synthesis workflows.

Synthesis

  • Route1
    • null|null
      3017-71-8
    • null|null
      201230-82-2
    • ~89%
    • In-stock
      Tiglic acid|CS-W013715
      80-59-1

    References

    • Alper, Howard; Amer, Ibrahim; Vasapollo, Giuseppe Tetrahedron Letters, 1989 , vol. 30, # 20 p. 2615 - 2616
  • Route2
    • null|null
      1400908-83-9
    • ~98%
    • In-stock
      2-Methylbutanoic acid|CS-W001942
      116-53-0
    • In-stock
      Tiglic acid|CS-W013715
      80-59-1
    • null|null
      1400908-78-2

    References

    • Phytochemistry, , vol. 81, p. 165 - 174
  • Route3
    • null|null
      1400908-85-1
    • ~96%
    • In-stock
      2-Methylbutanoic acid|CS-W001942
      116-53-0
    • In-stock
      Tiglic acid|CS-W013715
      80-59-1
    • null|null
      1400908-79-3

    References

    • Phytochemistry, , vol. 81, p. 165 - 174

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.0372
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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