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CS-W001157 4
Total: USD 88.00

N-Benzylbis(2-chloroethyl)amine hydrochloride

  • CAS No. 10429-82-0

  • Cat. No. CS-M1267
  • Purity≥96%
  • MDL No.MFCD00185654
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-Benzylbis(2-chloroethyl)amine hydrochloride|CS-M1267

Structure of 10429-82-0

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Description

N-Benzylbis(2-chloroethyl)amine hydrochloride is a bifunctional alkylating agent featuring two reactive chloroethyl groups attached to a benzyl-substituted nitrogen. This structure enables efficient cross-linking of nucleophilic sites in biomolecules, particularly targeting DNA guanine residues. The hydrochloride salt form enhances solubility and stability under standard conditions, facilitating use in synthetic biology and medicinal chemistry workflows.

Application

N-Benzylbis(2-chloroethyl)amine hydrochloride serves as a versatile bifunctional electrophile in nucleophilic substitution reactions, enabling efficient synthesis of nitrogen-containing heterocycles and macrocyclic scaffolds. Its two reactive 2-chloroethyl arms facilitate rapid cyclization under mild conditions, offering high functional group tolerance and ease of purification. The benzyl group enhances solubility and stability, supporting its use in peptide conjugation, dendrimer assembly, and the construction of bioactive analogs.

General Information

  • CAS No. 10429-82-0
  • Cat. No. CS-M1267
  • Purity ≥96%
  • MDL No. MFCD00185654
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆Cl₃N
  • Molecular Weight None
  • Synonym(s) N-Benzyl-N,N-Di(2-Chloroethyl)Amine Hydrochloride
  • SMILES ClCCN(CCCl)CC1=CC=CC=C1.Cl

Computational Chemistry Data

  • TPSA   3.24
  • LogP   3.388
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   6

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS06,GHS08
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group :
Hazard Statements : H302-H314-H318-H331-H350
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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