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Structure of 10429-82-0
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N-Benzylbis(2-chloroethyl)amine hydrochloride is a bifunctional alkylating agent featuring two reactive chloroethyl groups attached to a benzyl-substituted nitrogen. This structure enables efficient cross-linking of nucleophilic sites in biomolecules, particularly targeting DNA guanine residues. The hydrochloride salt form enhances solubility and stability under standard conditions, facilitating use in synthetic biology and medicinal chemistry workflows.
N-Benzylbis(2-chloroethyl)amine hydrochloride serves as a versatile bifunctional electrophile in nucleophilic substitution reactions, enabling efficient synthesis of nitrogen-containing heterocycles and macrocyclic scaffolds. Its two reactive 2-chloroethyl arms facilitate rapid cyclization under mild conditions, offering high functional group tolerance and ease of purification. The benzyl group enhances solubility and stability, supporting its use in peptide conjugation, dendrimer assembly, and the construction of bioactive analogs.
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GHS Pictogram :
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GHS No : GHS05,GHS06,GHS08
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314-H318-H331-H350
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: