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5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine

  • CAS No. 1034667-22-5

  • Cat. No. CS-0037437
  • Purity≥98%
  • MDL No.MFCD15526909

*For research and further manufacturing use only, not for direct human use.

5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine|CS-0037437

Structure of 1034667-22-5

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General Information

  • CAS No. 1034667-22-5
  • Cat. No. CS-0037437
  • Purity ≥98%
  • MDL No. MFCD15526909
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅FN₄
  • Molecular Weight 152.13
  • Synonym(s) 5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-amine
  • SMILES C1=C(C=NC2=NNC(=C12)N)F

Synthesis

  • Route1

    References

    • VERTEX PHARMACEUTICALS INCORPORATED Patent: WO2008/112642 A1, 2008 ; Location in patent: Page/Page column 51-52 ; WO 2008/112642 A1
  • Route2

    References

    • US2011/20377 A1, ; US 20110020377 A1
  • Route3
    • 2-Chloro-5-fluoronicotinamide|CS-0135776
      75302-64-6
    • ~%
    • In-stock
      5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine|CS-0037437
      1034667-22-5

    References

    • US2011/20377 A1, ; US 20110020377 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   67.59
  • LogP   0.6792
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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