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CS-W001157 4
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2-Chloro-5-fluoronicotinamide

  • CAS No. 75302-64-6

  • Cat. No. CS-0135776
  • Purity≥95%
  • MDL No.MFCD16658704

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5-fluoronicotinamide|CS-0135776

Structure of 75302-64-6

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General Information

  • CAS No. 75302-64-6
  • Cat. No. CS-0135776
  • Purity ≥95%
  • MDL No. MFCD16658704
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄ClFN₂O
  • Molecular Weight 174.56
  • Synonym(s) 3-Pyridinecarboxamide, 2-chloro-5-fluoro-
  • SMILES O=C(C1=CC(F)=CN=C1Cl)N

Synthesis

  • Route1

    References

    • VERTEX PHARMACEUTICALS INCORPORATED Patent: US2011/20377 A1, 2011 ; Location in patent: Page/Page column 12; 13 ; US 20110020377 A1
  • Route2
    • null|null
      1020849-13-1
    • ~92%
    • 2-Chloro-5-fluoronicotinamide|CS-0135776
      75302-64-6

    References

    • AstraZeneca AB; NPS PHARMACEUTICALS Patent: US2007/49578 A1, 2007 ; Location in patent: Page/Page column 22 ; US 20070049578 A1
  • Route3

    References

    • BAYER INTELLECTUAL PROPERTY GMBH; Follmann, Markus; Stasch, Johannes-Peter; Redlich, Gorden; Ackerstaff, Jens; Griebenow, Nils; Knorr, Andreas; Wunder, Frank; Li, Volkhart Min-Jian Patent: US2013/172372 A1, 2013 ; Location in patent: Paragraph 0242; 0243; 0244; 0245 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.98
  • LogP   0.973
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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