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CS-W001157 4
Total: USD 88.00

2-Chloro-5-fluoropyridine-3-carbonitrile

  • CAS No. 791644-48-9

  • Cat. No. CS-0051953
  • Purity≥98%
  • MDL No.MFCD15526908

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5-fluoropyridine-3-carbonitrile|CS-0051953

Structure of 791644-48-9

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General Information

  • CAS No. 791644-48-9
  • Cat. No. CS-0051953
  • Purity ≥98%
  • MDL No. MFCD15526908
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂ClFN₂
  • Molecular Weight 156.55
  • Synonym(s) 2-Chloro-5-fluoronicotinonitrile
  • SMILES FC1=CN=C(Cl)C(=C1)C#N

Synthesis

  • Route1
    • 2-Chloro-5-fluoronicotinamide|CS-0135776
      75302-64-6
    • ~94%
    • In-stock
      2-Chloro-5-fluoropyridine-3-carbonitrile|CS-0051953
      791644-48-9

    References

    • GLAXO GROUP LIMITED; BURY, Michael, Jonathan; CASILLAS, Linda, N.; CHARNLEY, Adam, Kenneth; DEMARTINO, Michael, P.; DONG, Xiaoyang; EIDAM, Patrick, M.; HAILE, Pamela, A.; MARQUIS, Robert, W., Jr.; RAMANJULU, Joshi, M.; ROMANO, Joseph, J.; SINGHAUS, Robert, R., Jr.; SHAH, Ami, Lakdawala; WANG, Gren Patent: WO2013/25958 A1, 2013 ; Location in patent: Page/Page column 57; 58 ;
  • Route2

    References

    • ARENA PHARMACEUTICALS, INC.; JONES, Robert M.; BUZARD, Daniel J.; HAN, Sangdon; KIM, Sun Hee; LEHMANN, Juerg; ZHU, Xiuwen Patent: WO2013/55910 A1, 2013 ; Location in patent: Page/Page column 106; 107 ;
  • Route3

    References

    • US2011/20377 A1, ; US 20110020377 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.68
  • LogP   1.74578
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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