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CS-W001157 4
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5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine

  • CAS No. 405224-24-0

  • Cat. No. CS-W022298
  • Purity≥97%
  • MDL No.MFCD08059261

*For research and further manufacturing use only, not for direct human use.

5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine|CS-W022298

Structure of 405224-24-0

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General Information

  • CAS No. 405224-24-0
  • Cat. No. CS-W022298
  • Purity ≥97%
  • MDL No. MFCD08059261
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrN₄
  • Molecular Weight 213.04
  • Synonym(s) 5-Bromo-1H-pyrazole[3,4-b]pyridin-3-amine
  • SMILES BrC1=CN=C2C(=C1)C(=N[NH]2)N

Synthesis

  • Route1

    References

    • VERTEX PHARMACEUTICALS INCORPORATED Patent: WO2007/59219 A1, 2007 ; Location in patent: Page/Page column 54-55 ; WO 2007/059219 A1
  • Route2

    References

    • PIERRE FABRE MEDICAMENT; Sokoloff, Pierre; Cachoux, Frédéric Patent: EP2689778 A1, 2014 ; Location in patent: Paragraph 0186 ;
  • Route3
    • 3-Pyridinecarbonitrile, 2-chloro-|CS-0654103
      6602-54-6
    • ~%
    • In-stock
      5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine|CS-W022298
      405224-24-0

    References

    • PIERRE FABRE MEDICAMENT; Sokoloff, Pierre; Cachoux, Frédéric Patent: EP2689778 A1, 2014 ; Title/Abstract Full Text Show Details PIERRE FABRE MEDICAMENT; Kruczynski, Anna; Creancier, Laurent; Kaloun, El Bachir; Bedjeguelal, Karim; Rabot, Rémi Patent: EP2689779 A1, 2014 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   67.59
  • LogP   1.3026
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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