Lot numbers can be found on the outside label of a product:
6-bromo-2,4-dichloroquinazoline
-
CAS No. 102393-82-8
- Cat. No. CS-W001034
- Purity≥95%
- MDL No.MFCD09744007
*For research and further manufacturing use only, not for direct human use.
Structure of 102393-82-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 102393-82-8
- Cat. No. CS-W001034
- Purity ≥95%
- MDL No. MFCD09744007
- Storage -20°C, sealed storage, away from moisture
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₃BrCl₂N₂
- Molecular Weight 277.93
- Synonym(s) Quinazoline, 6-bromo-2,4-dichloro-
- SMILES Clc1nc(Cl)c2cc(Br)ccc2n1
Description
6-Bromo-2,4-dichloroquinazoline is a halogenated quinazoline derivative featuring bromine at the 6-position and chlorine substituents at the 2- and 4-positions. This electron-deficient scaffold integrates readily into C–N coupling reactions, serving as a key building block for kinase inhibitors and bioactive heterocycles. The molecule exhibits enhanced reactivity in palladium-catalyzed transformations due to its strategic halogen placement.
Application
6-Bromo-2,4-dichloroquinazoline serves as a versatile building block for the synthesis of substituted quinazolines via palladium-catalyzed cross-coupling reactions. The bromo group enables efficient Suzuki, Stille, or Negishi coupling, while the two chlorine atoms provide orthogonal reactivity for sequential functionalization. This compound exhibits good bench stability and facilitates the construction of complex heterocyclic scaffolds relevant to medicinal chemistry and agrochemical development.
Synthesis
-
Route1
-
In-stock
88145-89-5 - ~98%
-
In-stock
102393-82-8
References
-
Volzhina, O. N.; Azimov, V. A.; Medvedev, B. A.; Kazakov, A. A.; Zhikhareva, G. P.; et al. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 7 p. 478 - 483 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 7 p. 802 - 807
-
-
Route2
-
32315-10-9 -
In-stock
39263-32-6 - ~93%
-
In-stock
102393-82-8
References
-
Li, Zhenhua; Wu, Danli; Zhong, Weihui Heterocycles, 2012 , vol. 85, # 6 p. 1417 - 1426
-
-
Route3
-
![6-Bromo-2H-benzo[e][1,3]oxazine-2,4(3H)-dione|CS-0138305](https://file.chemscene.com/productPIC/CS-0138305.gif)
24088-82-2 - ~%
-
In-stock
102393-82-8
References
-
WO2009/143058 A1, ; Page/Page column 69 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 25.78
- LogP 3.6991
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6-bromo-2,4-dichloroquinazoline sigma6-bromo-2,4-dichloroquinazoline manufacturer6-bromo-2,4-dichloroquinazoline price6-bromo-2,4-dichloroquinazoline structure6-bromo-2,4-dichloroquinazoline SDSbuy 6-bromo-2,4-dichloroquinazoline6-bromo-2,4-dichloroquinazoline supplier6-bromo-2,4-dichloroquinazoline uses6-bromo-2,4-dichloroquinazoline molecular weightprice of 6-bromo-2,4-dichloroquinazoline6-bromo-2,4-dichloroquinazoline chemical name formula of 6-bromo-2,4-dichloroquinazoline