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CS-W001157 4
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Methyl 6-aminopyridazine-3-carboxylate

  • CAS No. 98140-96-6

  • Cat. No. CS-0039253
  • Molecule weight153.14
  • Purity≥96%
  • MDL No.MFCD11226154

*For research and further manufacturing use only, not for direct human use.

Methyl 6-aminopyridazine-3-carboxylate|CS-0039253

Structure of 98140-96-6

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General Information

  • CAS No. 98140-96-6
  • Cat. No. CS-0039253
  • Purity ≥96%
  • MDL No. MFCD11226154
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇N₃O₂
  • Molecular Weight 153.14
  • Synonym(s) Methyl 6-amino-3-pyridazinecarboxylate
  • SMILES O=C(C1=NN=C(N)C=C1)OC

Description

Methyl 6-aminopyridazine-3-carboxylate features a polar pyridazine core with complementary amine and ester functionalities, enabling direct incorporation into diverse heterocyclic scaffolds. This bench-stable derivative facilitates efficient access to bioactive nitrogen-rich compounds through straightforward derivatization under standard conditions.

Application

Methyl 6-aminopyridazine-3-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridazinone-based scaffolds. The ortho-diamino functionality facilitates diverse transformations, including cyclizations, metal-catalyzed couplings, and electrophilic substitutions. Its stability under standard reaction conditions and ease of purification make it well-suited for iterative synthesis workflows.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      3-Amino-6-chloropyridazine|CS-W019657
      5469-69-2
    • null|null
      201230-82-2
    • ~%
    • In-stock
      Methyl 6-aminopyridazine-3-carboxylate|CS-0039253
      98140-96-6

    References

    • WO2013/67710 A1, ; Page/Page column 36 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.1
  • LogP   -0.1546
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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