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CS-W001157 4
Total: USD 88.00

3-Aminopyridazine-6-carboxylic acid

  • CAS No. 59772-58-6

  • Cat. No. CS-W003307
  • Molecule weight139.11
  • Purity≥95%
  • MDL No.MFCD06658328

*For research and further manufacturing use only, not for direct human use.

3-Aminopyridazine-6-carboxylic acid|CS-W003307

Structure of 59772-58-6

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General Information

  • CAS No. 59772-58-6
  • Cat. No. CS-W003307
  • Purity ≥95%
  • MDL No. MFCD06658328
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅N₃O₂
  • Molecular Weight 139.11
  • Synonym(s) Acide 6-aminopyridazine-3-carboxylique
  • SMILES Nc1ccc(nn1)C(=O)O

Description

3-Aminopyridazine-6-carboxylic acid features a conjugated heterocyclic core bearing both amino and carboxylic acid functional groups, enabling versatile coupling reactions. This dual functionality supports integration into bioconjugates, pharmaceutical scaffolds, and advanced materials, particularly in contexts requiring hydrogen bonding or metal coordination.

Application

3-Aminopyridazine-6-carboxylic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling direct incorporation into bioactive scaffolds via amide bond formation or cyclization. Its dual functionality—readily modifiable amino and carboxylic acid groups—supports orthogonal derivatization, while the pyridazine core provides structural rigidity and hydrogen-bonding capacity relevant to target binding. The compound exhibits bench stability and facilitates purification through crystallization or ion-exchange chromatography, making it well-suited for scalable synthesis and process development.

Synthesis

  • Route1

    References

    • Nippon Kagaku Zasshi, , vol. 78, p. 577,579, 580 Chem.Abstr., , p. 5275

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   89.1
  • LogP   -0.243
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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