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CS-W001157 4
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Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate

  • CAS No. 95928-49-7

  • Cat. No. CS-0045763
  • Purity≥97%
  • MDL No.MFCD09863163
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate|CS-0045763

Structure of 95928-49-7

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Description

Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate serves as a key scaffold in heterocyclic synthesis, featuring a conjugated enone system and a pendant ester group. This bench-stable compound integrates readily into multistep transformations, enabling efficient access to pyrimidine-based architectures through nucleophilic addition and cyclization pathways.

Application

Ethyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine scaffolds prevalent in medicinal chemistry. Its enolizable carbonyl and electron-deficient C5 position facilitate nucleophilic addition and condensation reactions. The molecule exhibits bench stability, ease of purification, and compatibility with standard reaction conditions, making it ideal for constructing biologically relevant frameworks through modular synthetic approaches.

General Information

  • CAS No. 95928-49-7
  • Cat. No. CS-0045763
  • Purity ≥97%
  • MDL No. MFCD09863163
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₃
  • Molecular Weight 168.15
  • Synonym(s) Ethyl 2-hydroxypyrimidine-5-carboxylate
  • SMILES O=C(C1=CNC(N=C1)=O)OCC

Computational Chemistry Data

  • TPSA   72.05
  • LogP   -0.0534
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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