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CS-W001157 4
Total: USD 88.00

Fmoc-Phe(4-NH2)-OH

  • CAS No. 95753-56-3

  • Cat. No. CS-W011698
  • Purity≥98%
  • MDL No.MFCD00237664

*For research and further manufacturing use only, not for direct human use.

Fmoc-Phe(4-NH2)-OH|CS-W011698

Structure of 95753-56-3

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General Information

  • CAS No. 95753-56-3
  • Cat. No. CS-W011698
  • Purity ≥98%
  • MDL No. MFCD00237664
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₂N₂O₄
  • Molecular Weight 402.44
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CC1=CC=C(N)C=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

Fmoc-Phe(4-NH2)-OH features a para-aminophenyl side chain enabling direct conjugation in peptide synthesis. This derivative integrates readily into C-terminal extensions, offering enhanced solubility and stability under standard coupling conditions. The Fmoc group ensures efficient deprotection during sequential elongation.

Synthesis

  • Route1

    References

    • Singh, Preeti; Hurrell, Craig R.; Findlay, John B. C.; Fishwick, Colin W. G. Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 6 p. 715 - 718
  • Route2

    References

    • Tetrahedron Letters, , vol. 40, # 36 p. 6557 - 6560
  • Route3

    References

    • Tetrahedron Letters, , vol. 40, # 36 p. 6557 - 6560

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   3.8032
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   6

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