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(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-aminophenyl)propanoic acid

  • CAS No. 324017-21-2

  • Cat. No. CS-0063912
  • Purity≥97%
  • MDL No.MFCD02682658

*For research and further manufacturing use only, not for direct human use.

(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-aminophenyl)propanoic acid|CS-0063912

Structure of 324017-21-2

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General Information

  • CAS No. 324017-21-2
  • Cat. No. CS-0063912
  • Purity ≥97%
  • MDL No. MFCD02682658
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₂N₂O₄
  • Molecular Weight 402.44
  • Synonym(s) Fmoc-4-amino-D-phenylalanine
  • SMILES O=C(O)[C@@H](CC1=CC=C(N)C=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-aminophenyl)propanoic acid features a chiral backbone with a fluorenylmethoxycarbonyl (Fmoc) protecting group, enabling direct incorporation into peptide synthesis. The para-aminophenyl side chain provides a reactive handle for conjugation and structural diversity in bioconjugate applications. This bench-stable derivative supports efficient coupling under standard conditions.

Application

(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-aminophenyl)propanoic acid serves as a versatile chiral building block for the synthesis of bioactive peptides and peptidomimetics. The fluorenylmethoxycarbonyl (Fmoc) group enables efficient, orthogonal protection during solid-phase peptide synthesis, while the para-aminophenyl side chain offers a handle for further functionalization. Bench-stable and readily purified by flash chromatography, it facilitates high-yielding coupling reactions under standard conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   3.8032
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   6

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