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Structure of 957346-62-2
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5-Bromothiazole-2-carboxylic acid features a brominated thiazole ring fused to a carboxylic acid group, offering a potent electrophilic handle for cross-coupling and derivatization. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds and bioactive molecules, where the electron-deficient thiazole core enhances reactivity in nucleophilic substitution and metal-catalyzed transformations.
5-Bromothiazole-2-carboxylic acid serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the 5-position via palladium-catalyzed cross-coupling reactions. The carboxylic acid group facilitates derivatization through amide bond formation or esterification, while the thiazole core provides metabolic stability and favorable pharmacophore properties. Bench-stable and compatible with standard synthetic workflows, it functions effectively in the construction of heterocyclic scaffolds for drug discovery and advanced organic synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: