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CS-W001157 4
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(4-Chloro-2-hydroxyphenyl)boronic acid

  • CAS No. 1238196-66-1

  • Cat. No. CS-0112194
  • Purity≥98%
  • MDL No.MFCD18383546

*For research and further manufacturing use only, not for direct human use.

(4-Chloro-2-hydroxyphenyl)boronic acid|CS-0112194

Structure of 1238196-66-1

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General Information

  • CAS No. 1238196-66-1
  • Cat. No. CS-0112194
  • Purity ≥98%
  • MDL No. MFCD18383546
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BClO₃
  • Molecular Weight 172.37
  • Synonym(s) 4-Chloro-2-hydroxyphenylboronic acid
  • SMILES OB(O)C1=CC=C(C=C1O)Cl

Description

This boronate moiety features a para-chlorinated hydroxyphenyl scaffold, enabling efficient coupling in Suzuki-Miyaura reactions. The electron-deficient aryl ring enhances reactivity, while the bench-stable boronic acid functionality simplifies handling and integration into complex synthetic sequences.

Application

(4-Chloro-2-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The boronic acid functionality exhibits good bench stability and compatibility with diverse functional groups, facilitating the construction of substituted biaryls and heterocyclic scaffolds relevant to medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   60.69
  • LogP   -0.2746
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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