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N1-(Imidazo[1,2-a]pyrazin-8-yl)ethane-1,2-diamine

  • CAS No. 956722-44-4

  • Cat. No. CS-0083978
  • Molecule weight177.21
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N1-(Imidazo[1,2-a]pyrazin-8-yl)ethane-1,2-diamine|CS-0083978

Structure of 956722-44-4

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General Information

  • CAS No. 956722-44-4
  • Cat. No. CS-0083978
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁N₅
  • Molecular Weight 177.21
  • Synonym(s) N'-imidazo[1,2-a]pyrazin-8-ylethane-1,2-diamine
  • SMILES NCCNC1=NC=CN2C1=NC=C2

Description

N1-(Imidazo[1,2-a]pyrazin-8-yl)ethane-1,2-diamine features a rigid fused heterocyclic core paired with a flexible diamine side chain, enabling versatile coordination in transition metal complexes. This scaffold integrates electron-rich imidazopyrazine and primary amine functionalities, offering enhanced solubility and stability under standard bench conditions.

Application

N1-(Imidazo[1,2-a]pyrazin-8-yl)ethane-1,2-diamine serves as a versatile bifunctional building block for constructing nitrogen-rich heterocycles. Its imidazo[1,2-a]pyrazin scaffold enables robust coordination in transition metal catalysis, while the adjacent ethane-1,2-diamine moiety facilitates conjugation via amide or urea linkages. The compound exhibits good bench stability and simplifies purification in multistep syntheses, making it well-suited for medicinal chemistry campaigns targeting kinase inhibitors and other bioactive scaffolds.

Safety Information

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Computational Chemistry Data

  • TPSA   68.24
  • LogP   0.0999
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   3

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