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CS-W001157 4
Total: USD 88.00

Methyl 2-chloroquinazoline-7-carboxylate

  • CAS No. 953039-79-7

  • Cat. No. CS-0046212
  • Purity≥97%
  • MDL No.MFCD12031313

*For research and further manufacturing use only, not for direct human use.

Methyl 2-chloroquinazoline-7-carboxylate|CS-0046212

Structure of 953039-79-7

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General Information

  • CAS No. 953039-79-7
  • Cat. No. CS-0046212
  • Purity ≥97%
  • MDL No. MFCD12031313
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇ClN₂O₂
  • Molecular Weight 222.63
  • Synonym(s) 7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester
  • SMILES COC(=O)C1=CC=C2C=NC(Cl)=NC2=C1

Synthesis

  • Route1
    • Methyl 2,4-dichloroquinazoline-7-carboxylate|CS-0106171
      174074-89-6
    • ~65%
    • Methyl 2-chloroquinazoline-7-carboxylate|CS-0046212
      953039-79-7

    References

    • PFIZER PRODUCTS INC. Patent: WO2007/125405 A2, 2007 ; Location in patent: Page/Page column 20; 47; 54 ; WO 2007/125405 A2
  • Route2
    • Methyl 2-oxo-1,2-dihydroquinazoline-7-carboxylate|CS-0488380
      953039-78-6
    • ~61%
    • Methyl 2-chloroquinazoline-7-carboxylate|CS-0046212
      953039-79-7

    References

    • NOVARTIS VACCINES and DIAGNOSTICS, INC. Patent: WO2007/117607 A2, 2007 ; Location in patent: Page/Page column 341 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.08
  • LogP   2.0698
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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