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Structure of 1036755-96-0
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Methyl 2-chloroquinazoline-6-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a chlorine substituent at the 2-position and a methyl ester group at the 6-position. This configuration enables direct coupling in transition-metal-catalyzed cross-coupling reactions and facilitates downstream derivatization via hydrolysis or nucleophilic substitution.
Methyl 2-chloroquinazoline-6-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to quinazoline-based scaffolds. The chloro group at the 2-position facilitates nucleophilic substitution reactions, while the ester functionality supports selective transformations and downstream derivatization. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for use in multi-step syntheses targeting kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352
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Lot numbers can be found on the outside label of a product: