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CS-W001157 4
Total: USD 88.00

Methyl 2-(triphenylphosphoranylidene)acetate

  • CAS No. 2605-67-6

  • Cat. No. CS-W008922
  • Purity≥95%
  • MDL No.MFCD00008455

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(triphenylphosphoranylidene)acetate|CS-W008922

Structure of 2605-67-6

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General Information

  • CAS No. 2605-67-6
  • Cat. No. CS-W008922
  • Purity ≥95%
  • MDL No. MFCD00008455
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₉O₂P
  • Molecular Weight 334.36
  • Synonym(s) None
  • SMILES O=C(C=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)OC

Description

Wittig reagent for the two-carbon homologation of aldehydes to ,-unsaturated esters. Also used in an efficient synthesis of pyrazoles via reaction with methyl diazoacetate in the presence of triethylamine.

Application

Methyl 2-(triphenylphosphoranylidene)acetate serves as a stable, bench-ready phosphorus ylide reagent enabling reliable Wittig reactions. It facilitates efficient olefination of aldehydes and ketones under mild conditions, offering high stereoselectivity for (Z)-alkenes in standard synthetic workflows. Its compatibility with diverse functional groups and ease of purification make it a practical choice for constructing conjugated systems and complex molecular architectures in organic synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.9557
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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