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CS-W001157 4
Total: USD 88.00

Ethyl (triphenylphosphoranylidene) acetate

  • CAS No. 1099-45-2

  • Cat. No. CS-M0973
  • Purity≥95%
  • MDL No.MFCD00009183

*For research and further manufacturing use only, not for direct human use.

Ethyl (triphenylphosphoranylidene) acetate|CS-M0973

Structure of 1099-45-2

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General Information

  • CAS No. 1099-45-2
  • Cat. No. CS-M0973
  • Purity ≥95%
  • MDL No. MFCD00009183
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₁O₂P
  • Molecular Weight 348.38
  • Synonym(s) None
  • SMILES O=C(OCC)C=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Description

3-Chloro-4-iodopyridine, can be used for the preparation of difluoromethylated pyridines. It is also an intermediate for the synthesis of 5-Chloro-4--2-pyridinecarboxylic Acid.

Synthesis

  • Route1
    • null|null
      105-36-2
    • null|null
      603-35-0
    • ~97%
    • In-stock
      Ethyl (triphenylphosphoranylidene) acetate|CS-M0973
      1099-45-2

    References

    • Mondal, Sayantan; Mohamed, Rana K.; Manoharan, Mariappan; Phan, Hoa; Alabugin, Igor V. Organic Letters, 2013 , vol. 15, # 22 p. 5650 - 5653
  • Route2

    References

    • Ngwendson, Julius N.; Schultze, Cassandra M.; Bollinger, Jordan W.; Banerjee, Anamitro Canadian Journal of Chemistry, 2008 , vol. 86, # 7 p. 668 - 675
  • Route3
    • null|null
      105-36-2
    • In-stock
      1,4-Cyclohexanedione|CS-W011270
      637-88-7
    • ~77%
    • In-stock
      Ethyl (triphenylphosphoranylidene) acetate|CS-M0973
      1099-45-2

    References

    • Medicines for Malaria Venture MMV International Centre Cointrin Patent: US6486199 B1, 2002 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H373-H411
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   3.3458
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   5

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