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CS-W001157 4
Total: USD 88.00

6-Bromo-2-chloro-8-fluoroquinazoline

  • CAS No. 953039-25-3

  • Cat. No. CS-0053929
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-2-chloro-8-fluoroquinazoline|CS-0053929

Structure of 953039-25-3

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General Information

  • CAS No. 953039-25-3
  • Cat. No. CS-0053929
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₃BrClFN₂
  • Molecular Weight 261.48
  • Synonym(s) Quinazoline, 6-bromo-2-chloro-8-fluoro-
  • SMILES FC1=CC(Br)=CC2=CN=C(Cl)N=C12

Synthesis

  • Route1
    • 6-Bromo-8-fluoroquinazolin-2(1H)-one|CS-0488374
      1036756-15-6
    • ~89%
    • 6-Bromo-2-chloro-8-fluoroquinazoline|CS-0053929
      953039-25-3

    References

    • BLUEPRINT MEDICINES; BIFULCO, Neil, Jr.; BROOIJMANS, Natasja; HODOUS, Brian, L.; KIM, Joseph, L.; MIDUTURU, Chandrasekhar, V. Patent: WO2014/11900 A2, 2014 ; Location in patent: Page/Page column 77; 79 ;
  • Route2

    References

    • BLUEPRINT MEDICINES; BIFULCO, Neil, Jr.; BROOIJMANS, Natasja; HODOUS, Brian, L.; KIM, Joseph, L.; MIDUTURU, Chandrasekhar, V. Patent: WO2014/11900 A2, 2014 ;
  • Route3

    References

    • BLUEPRINT MEDICINES; BIFULCO, Neil, Jr.; BROOIJMANS, Natasja; HODOUS, Brian, L.; KIM, Joseph, L.; MIDUTURU, Chandrasekhar, V. Patent: WO2014/11900 A2, 2014 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   3.1848
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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