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CS-W001157 4
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(6-Methoxybenzofuran-2-yl)boronic acid

  • CAS No. 952737-54-1

  • Cat. No. CS-W021122
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(6-Methoxybenzofuran-2-yl)boronic acid|CS-W021122

Structure of 952737-54-1

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General Information

  • CAS No. 952737-54-1
  • Cat. No. CS-W021122
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BO₄
  • Molecular Weight 191.98
  • Synonym(s) 6-methoxybenzofuran-2-ylboronic acid
  • SMILES COC1=CC=C2C=C(B(O)O)OC2=C1

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized heterocycles with high efficiency. The methoxy group enhances solubility and stabilizes the reactive intermediate, while the benzofuran scaffold provides a rigid, electron-rich platform for downstream derivatization.

Application

(6-Methoxybenzofuran-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl architectures. Its bench-stable nature and tolerance to common functional groups facilitate reliable synthesis of complex heterocyclic systems. The methoxy-substituted benzofuran core provides structural diversity relevant to medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • In-stock
      6-Methoxybenzofuran|CS-0150275
      50551-63-8
    • null|null
      5419-55-6
    • ~%
    • In-stock
      (6-Methoxybenzofuran-2-yl)boronic acid|CS-W021122
      952737-54-1

    References

    • AUCKLAND UNISERVICES LIMITED Patent: WO2007/117161 A1, 2007 ; Location in patent: Page/Page column 19-20 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   62.83
  • LogP   0.1212
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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